Development and validation of automatic solid phase extraction methods for the determination of iodinated X-ray contrast media in influents and effluents of waste water treatment plants
Engelsberg, Kathrin (2009)
2009
All rights reserved. This publication is copyrighted. You may download, display and print it for Your own personal use. Commercial use is prohibited.
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:amk-202405028764
https://urn.fi/URN:NBN:fi:amk-202405028764
Tiivistelmä
This study is related to laboratory analysis and measurement methods used in detection of trace components in the environmental sector. The purpose of this work was to develop and validate an automatic solid phase extraction (SPE) method for the determination of iodinated contrast media (ICM) in influents and effluents of waste water treatment plants.
The system used for sample pre-treatment was a manual solid phase extraction system by Baker. The procedure was adapted to an automatic solid phase extraction system by Horizon. The samples from the waste water pilot plant were analyzed with a liquid chromatography- triple quadrupole tandem mass spectrometry system with multiple reaction monitoring mode.
The result of this work was an improved automatic solid phase extraction method for waste water samples containing iodinated contrast media. Due to the lack of a proper speed disk material for the analytes, the SPE process was carried out at the automatic system with a cartridge and should be further optimized. The ICM were found in range between 0.25 - 52 µg/L in the waste water treatment plant.
The system used for sample pre-treatment was a manual solid phase extraction system by Baker. The procedure was adapted to an automatic solid phase extraction system by Horizon. The samples from the waste water pilot plant were analyzed with a liquid chromatography- triple quadrupole tandem mass spectrometry system with multiple reaction monitoring mode.
The result of this work was an improved automatic solid phase extraction method for waste water samples containing iodinated contrast media. Due to the lack of a proper speed disk material for the analytes, the SPE process was carried out at the automatic system with a cartridge and should be further optimized. The ICM were found in range between 0.25 - 52 µg/L in the waste water treatment plant.