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Pre-Analytical Errors in Blood Sample Collection : a narrative review focus on hematology testing

Prasai, Manisha (2025)

 
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Prasai, Manisha
2025
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Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:amk-2025121737486
Tiivistelmä
Almost all clinical decisions are based on analytical results. There are three critical phases in the analysis of laboratory tests which take place before, during, and after the laboratory analysis. This thesis is dedicated to the detection of errors that occur at the pre analytical stage and its following effect on the test outcomes in the hematology laboratories. Most of the pre-analytical errors are made prior to the actual test, which may result in wrong diagnosis and slow treatment. Among the most widespread ones are ineffective management and incorrect labeling.

The current research is based on the literature review that involves both qualitative and quantitative studies. A total of twenty-seven articles published in 2010-2025 were chosen, mostly in the PubMed database and the site of the International Journal of Biomedical Laboratory Science (IJBLS). The review focuses on the main questions: What are the most frequent mistakes that happen in blood sample
collection? How do pre-analytical errors affect the results of hematology? What can be done to minimize pre-analytical errors?

The review shows that clinical errors may be significantly reduced with the help of proper training of the staff and ensuring the clarity of communication. This is especially important in hematology laboratories where the integrity of samples is of paramount importance. Even small mistakes can cause great complications. All the personnel should be aware of the importance of every step in the workflow. The present review focuses on pre-analytical errors and following the set protocols, the errors can be minimized significantly.
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